ೳ Free  Format Kindle ┪ The Immortal Life of Henrietta Lacks eBook: Rebecca Skloot: Amazon.fr: Amazon Media EU  S.à r.l.  ᘔ ePUB Author Rebecca Skloot ᪔ ೳ Free Format Kindle ┪ The Immortal Life of Henrietta Lacks eBook: Rebecca Skloot: Amazon.fr: Amazon Media EU S.à r.l. ᘔ ePUB Author Rebecca Skloot ᪔ PROLOGUEThe Woman in the PhotographTheres a photo on my wall of a woman Ive never met, its left corner torn and patched together with tape She looks straight into the camera and smiles, hands on hips, dress suit neatly pressed, lips painted deep red Its the late 1940s and she hasnt yet reached the age of thirty Her light brown skin is smooth, her eyes still young and playful, oblivious to the tumor growing inside hera tumor that would leave her five children motherless and change the future of medicine Beneath the photo, a caption says her name is Henrietta Lacks, Helen Lane or Helen Larson.No one knows who took that picture, but its appeared hundreds of times in magazines and science textbooks, on blogs and laboratory walls Shes usually identified as Helen Lane, but often she has no name at all Shes simply called HeLa, the code name given to the worlds first immortal human cells her cells, cut from her cervix just months before she died.Her real name is Henrietta Lacks.Ive spent years staring at that photo, wondering what kind of life she led, what happened to her children, and what shed think about cells from her cervix living on foreverbought, sold, packaged, and shipped by the trillions to laboratories around the world Ive tried to imagine how shed feel knowing that her cells went up in the first space missions to see what would happen to human cells in zero gravity, or that they helped with some of the most important advances in medicine the polio vaccine, chemotherapy, cloning, gene mapping, in vitro fertilization Im pretty sure that shelike most of uswould be shocked to hear that there are trillions of her cells growing in laboratories now than there ever were in her body.Theres no way of knowing exactly how many of Henriettas cells are alive today One scientist estimates that if you could pile all HeLa cells ever grown onto a scale, theyd weigh than 50 million metric tonsan inconceivable number, given that an individual cell weighs almost nothing Another scientist calculated that if you could lay all HeLa cells ever grown end to end, theyd wrap around the Earth at least three times, spanning than 350 million feet In her prime, Henrietta herself stood only a bit over five feet tall.I first learned about HeLa cells and the woman behind them in 1988, thirty seven years after her death, when I was sixteen and sitting in a community college biology class My instructor, Donald Defler, a gnomish balding man, paced at the front of the lecture hall and flipped on an overhead projector He pointed to two diagrams that appeared on the wall behind him They were schematics of the cell reproduction cycle, but to me they just looked like a neon colored mess of arrows, squares, and circles with words I didnt understand, like MPF Triggering a Chain Reaction of Protein Activations.I was a kid whod failed freshman year at the regular public high school because she never showed up Id transferred to an alternative school that offered dream studies instead of biology, so I was taking Deflers class for high school credit, which meant that I was sitting in a college lecture hall at sixteen with words like mitosis and kinase inhibitors flying around I was completely lost.Do we have to memorize everything on those diagrams one student yelled.Yes, Defler said, we had to memorize the diagrams, and yes, theyd be on the test, but that didnt matter right then What he wanted us to understand was that cells are amazing things There are about one hundred trillion of them in our bodies, each so small that several thousand could fit on the period at the end of this sentence They make up all our tissuesmuscle, bone, bloodwhich in turn make up our organs.Under the microscope, a cell looks a lot like a fried egg It has a white the cytoplasm thats full of water and proteins to keep it fed, and a yolk the nucleus that holds all the genetic information that makes you you The cytoplasm buzzes like a New York City street Its crammed full of molecules and vessels endlessly shuttling enzymes and sugars from one part of the cell to another, pumping water, nutrients, and oxygen in and out of the cell All the while, little cytoplasmic factories work 24 7, cranking out sugars, fats, proteins, and energy to keep the whole thing running and feed the nucleus The nucleus is the brains of the operation inside every nucleus within each cell in your body, theres an identical copy of your entire genome That genome tells cells when to grow and divide and makes sure they do their jobs, whether thats controlling your heartbeat or helping your brain understand the words on this page.Defler paced the front of the classroom telling us how mitosisthe process of cell divisionmakes it possible for embryos to grow into babies, and for our bodies to create new cells for healing wounds or replenishing blood weve lost It was beautiful, he said, like a perfectly choreographed dance.All it takes is one small mistake anywhere in the division process for cells to start growing out of control, he told us Just one enzyme misfiring, just one wrong protein activation, and you could have cancer Mitosis goes haywire, which is how it spreads.We learned that by studying cancer cells in culture, Defler said He grinned and spun to face the board, where he wrote two words in enormous print HENRIETTA LACKS.Henrietta died in 1951 from a vicious case of cervical cancer, he told us But before she died, a surgeon took samples of her tumor and put them in a petri dish Scientists had been trying to keep human cells alive in culture for decades, but they all eventually died Henriettas were different they reproduced an entire generation every twenty four hours, and they never stopped They became the first immortal human cells ever grown in a laboratory.Henriettas cells have now been living outside her body far longer than they ever lived inside it, Defler said If we went to almost any cell culture lab in the world and opened its freezers, he told us, wed probably find millionsif not billionsof Henriettas cells in small vials on ice.Her cells were part of research into the genes that cause cancer and those that suppress it they helped develop drugs for treating herpes, leukemia, influenza, hemophilia, and Parkinsons disease and theyve been used to study lactose digestion, sexually transmitted diseases, appendicitis, human longevity, mosquito mating, and the negative cellular effects of working in sewers Their chromosomes and proteins have been studied with such detail and precision that scientists know their every quirk Like guinea pigs and mice, Henriettas cells have become the standard laboratory workhorse.HeLa cells were one of the most important things that happened to medicine in the last hundred years, Defler said.Then, matter of factly, almost as an afterthought, he said, She was a black woman He erased her name in one fast swipe and blew the chalk from his hands Class was over.As the other students filed out of the room, I sat thinking, Thats it Thats all we get There has to be to the story. I followed Defler to his office.Where was she from I asked Did she know how important her cells were Did she have any children I wish I could tell you, he said, but no one knows anything about her.After class, I ran home and threw myself onto my bed with my biology textbook I looked up cell culture in the index, and there she was, a small parenthetical In culture, cancer cells can go on dividing indefinitely, if they have a continual supply of nutrients, and thus are said to be immortal A striking example is a cell line that has been reproducing in culture since 1951 Cells of this line are called HeLa cells because their original source was a tumor removed from a woman named Henrietta Lacks That was it I looked up HeLa in my parents encyclopedia, then my dictionary No Henrietta As I graduated from high school and worked my way through college toward a biology degree, HeLa cells were omnipresent I heard about them in histology, neurology, pathology I used them in experiments on how neighboring cells communicate But after Mr Defler, no one mentioned Henrietta When I got my first computer in the mid nineties and started using the Internet, I searched for information about her, but found only confused snippets most sites said her name was Helen Lane some said she died in the thirties others said the forties, fifties, or even sixties Some said ovarian cancer killed her, others said breast or cervical cancer Eventually I tracked down a few magazine articles about her from the seventies Ebony quoted Henriettas husband saying, All I remember is that she had this disease, and right after she died they called me in the office wanting to get my permission to take a sample of some kind I decided not to let them Jet said the family was angryangry that Henriettas cells were being sold for twenty five dollars a vial, and angry that articles had been published about the cells without their knowledge It said, Pounding in the back of their heads was a gnawing feeling that science and the press had taken advantage of them The articles all ran photos of Henriettas family her oldest son sitting at his dining room table in Balti, looking at a genetics textbook Her middle son in military uniform, smiling and holding a baby But one picture stood out than any other in it, Henriettas daughter, Deborah Lacks, is surrounded by family, everyone smiling, arms around each other, eyes bright and excited Except Deborah She stands in the foreground looking alone, almost as if someone pasted her into the photo after the fact Shes twenty six years old and beautiful, with short brown hair and catlike eyes But those eyes glare at the camera, hard and serious The caption said the family had found out just a few months earlier that Henriettas cells were still alive, yet at that point shed been dead for twenty five years All of the stories mentioned that scientists had begun doing research on Henriettas children, but the Lackses didnt seem to know what that research was for They said they were being tested to see if they had the cancer that killed Henrietta, but according to the reporters, scientists were studying the Lacks family to learn about Henriettas cells The stories quoted her son Lawrence, who wanted to know if the immortality of his mothers cells meant that he might live forever too But one member of the family remained voiceless Henriettas daughter, Deborah As I worked my way through graduate school studying writing, I became fixated on the idea of someday telling Henriettas story At one point I even called directory assistance in Balti looking for Henriettas husband, David Lacks, but he wasnt listed I had the idea that Id write a book that was a biography of both the cells and the woman they came fromsomeones daughter, wife, and mother I couldnt have imagined it then, but that phone call would mark the beginning of a decadelong adventure through scientific laboratories, hospitals, and mental institutions, with a cast of characters that would include Nobel laureates, grocery store clerks, convicted felons, and a professional con artist While trying to make sense of the history of cell culture and the complicated ethical debate surrounding the use of human tissues in research, Id be accused of conspiracy and slammed into a wall both physically and metaphorically, and Id eventually find myself on the receiving end of something that looked a lot like an exorcism I did eventually meet Deborah, who would turn out to be one of the strongest and most resilient women Id ever known Wed form a deep personal bond, and slowly, without realizing it, Id become a character in her story, and she in mine Deborah and I came from very different cultures I grew up white and agnostic in the Pacific Northwest, my roots half New York Jew and half Midwestern Protestant Deborah was a deeply religious black Christian from the South I tended to leave the room when religion came up in conversation because it made me uncomfortable Deborahs family tended toward preaching, faith healings, and sometimes voodoo She grew up in a black neighborhood that was one of the poorest and most dangerous in the country I grew up in a safe, quiet middle class neighborhood in a predominantly white city and went to high school with a total of two black students I was a science journalist who referred to all things supernatural as woo woo stuff Deborah believed Henriettas spirit lived on in her cells, controlling the life of anyone who crossed its paths Including me How else do you explain why your science teacher knew her real name when everyone else called her Helen Lane Deborah would say She was trying to get your attention This thinking would apply to everything in my life when I married while writing this book, it was because Henrietta wanted someone to take care of me while I worked When I divorced, it was because shed decided he was getting in the way of the book When an editor who insisted I take the Lacks family out of the book was injured in a mysterious accident, Deborah said thats what happens when you piss Henrietta off The Lackses challenged everything I thought I knew about faith, science, journalism, and race Ultimately, this book is the result Its not only the story of HeLa cells and Henrietta Lacks, but of Henriettas familyparticularly Deborahand their lifelong struggle to make peace with the existence of those cells, and the science that made them possible.Oneof the most graceful and moving nonfiction books Ive read in a very long time The Immortal Life of Henrietta Lacks floods over you like a narrative dam break, as if someone had managed to distill and purify the addictive qualities of Erin Brockovich, Midnight in the Garden of Good and Evil and The Andromeda Strain it feels like the book Ms Skloot was born to write It signals the arrival of a raw but quite real talent.Dwight Garner, The New York TimesSkloot s vivid account begins with the life of Henrietta Lacks, who comes fully alive on the page Immortal Life reads like a novel Eric Roston, The Washington PostGrippingby turns heartbreaking, funny and unsettlingraises troubling questions about the way Mrs Lacks and her family were treated by researchers and about whether patients should control or have financial claims on tissue removed from their bodies.Denise Grady, New York TimesThe Immortal Life of Henrietta Lacks is a fascinating read and a ringing success It is a well written, carefully researched, complex saga of medical research, bioethics, and race in America Above all it is a human story of redemption for a family, torn by loss, and for a writer with a vision that would not let go.Douglas Whynott, The Boston GlobeRivetingraises important questions about medical ethicsIt s an amazing storyDeeply chilling Whether those uncountable HeLa cells are a miracle or a violation, Skloot tells their fascinating story at last with skill, insight and compassion Colette Bancroft, St Petersburg TimesThe history of HeLa is a rare and powerful combination of race, class, gender, medicine, bioethics, and intellectual property far rare is the writer than can so clearly fuse those disparate threads into a personal story so rich and compelling Rebecca Skloot has crafted a unique piece of science journalism that is impossible to put downor to forget Seed magazineNo one can say exactly where Henrietta Lacks is buried during the many years Rebecca Skloot spent working on this book, even Lackss hometown of Clover, Virginia, disappeared But that did not stop Skloot in her quest to exhume, and resurrect, the story of her heroine and her family What this important, invigorating book lays bare is how easily science can do wrong, especially to the poor The issues evoked here are giant who owns our bodies, the use and misuse of medical authority, the unhealed wounds of slavery and Skloot, with clarity and compassion, helps us take the long view This is exactly the sort of story that books were made to tellthorough, detailed, quietly passionate, and full of revelation.TED CONOVER, author of Newjack and The Routes of ManIts extremely rare when a reporters passion finds its match in a story Rarer still when the people in that story courageously join thatreporter in the search for what we most need to know about ourselves When this occurs with a moral journalist who is also a true writer, a human being with a heart capable of holding all of lifes damage and joy, the stars have aligned This is an extraordinary gift of a book, beautiful and devastatinga work of outstanding literary reportage Read it Its the best you will find in many many years.ADRIAN NICOLE LEBLANC, author of Random Family The Immortal Life of Henrietta Lacks brings to mind the work of Philip K Dick and Edgar Allan Poe But this tale is true Rebecca Skloot explores the racism and greed, the idealism and faith in science that helped to save thousands of lives butnearly destroyed a family This is an extraordinary book, haunting and beautifully told.ERIC SCHLOSSER, author of Fast Food NationSkloots book is wonderful deeply felt, gracefully written, sharply reported It is a story about science but, much , about life.SUSAN ORLEAN, author of The Orchid ThiefThis is a science biography like the world has never seen What if one of the great American women of modern science and medicine whose contribution underlay historic discoveries in genetics, the treatment and prevention of disease, reproduction, and the unraveling of the human genome was a self effacing African American tobacco farmer from the Deep South A devoted mother of five who was escorted briskly to the Jim Crow section of Johns Hopkins for her cancer treatments What if the untold millions of scientists, doctors, and patients enriched and healed by her gift never, to this day,knew her name What if her contribution was made without her knowledge or permission Ladies and gentlemen, meet Henrietta Lacks Chances are, at the level of your DNA, your inoculations, your physical health and microscopic well being, youve already been introduced MELISSA FAY GREENE, author of Praying for Sheetrock and There Is No Me Without YouHeartbreaking and powerful, unsettling yet compelling, The Immortal Life of Henrietta Lacks is a richly textured story of the hidden costs of scientific progress Deftly weaving together history, journalism and biography, Rebecca Skloot s sensitive account tells of the enduring, deeply personal sacrifice of this African American woman and her family and, at long last, restores a human face to the cell line that propelled 20th century biomedicine A stunning illustration of how race, gender and disease intersect to produce a unique form of social vulnerability, this is a poignant, necessary and brilliant book.ALONDRA NELSON, Columbia University editor of Technicolor Race, Technology and Everyday LifeRebecca Skloot has written a marvelous book so original that it defies easy description She traces the surreal journey that a tiny patch of cells belonging to Henrietta Lackss body took to the forefront of science At the same time, she tells the story of Lacks and her familywrestling the storms of the late twentieth century in Americawith rich detail, wit, and humanity The we read, the we realize that these are not two separate stories, but one tapestry Its part The Wire, part The Lives of the Cell, and all fascinating.CARL ZIMMER, author of Microcosm If virtues could be cultured like cells, Rebecca Skloots would be a fine place to startfrac34 a rare combination of compassion, courage, wisdom, and intelligence This book is extraordinary As a writer and a human being, Skloot stands way, way out there ahead of the pack.MARY ROACH, author of Stiff and Bonk The Immortal Life of Henrietta Lacks takes the reader on a remarkable journeycompassionate, troubling, funny, smartand irresistible Along the way, Rebecca Skloot will change the way you see medical science and lead you to wonder who we should value the researcher or the research subject Ethically fascinating and completely engagingI couldnt recommend it .DEBORAH BLUM, author of The Poisoners Handbook and The Monkey Wars and the Helen Firstbrook Franklin professor of journalism at the University of Wisconsin MadisonThis remarkable story of how the cervical cells of the late Henrietta Lacks, a poor black woman,enabled subsequent discoveriesfrom the polio vaccine to in vitro fertilization is extraordinary in itself the added portrayal of Lacks s full life makes the story come alive with her humanity and the palpable relationship between race, science, and exploitation.PAULA J GIDDINGS, author of Ida, A Sword Among Lions Elizabeth A Woodson 1922 Professor, Afro American Studies, Smith CollegeRebecca Skloots steadfast commitment to illuminating the life and contribution of Henrietta Lacks, one of the many vulnerable subjects used for scientific advancement, and the subsequent impact on her family is a testament to the power of solid investigative journalism Her deeply compelling account of one familys long and troubled relationship with Americas vast medical industrial complex is sure to become a cherished classic.ALLEN M HORNBLUM, author of Acres of Skin and Sentenced to ScienceWriting with a novelists artistry, a biologists expertise, and the zeal of an investigative reporter, Skloot tells a truly astonishing story of racism and poverty, science and conscience, spirituality and family driven by a galvanizing inquiry into the sanctity of the body and the very nature of the life force.BOOKLIST starred review Science journalist Skloot makes a remarkable debut with this multilayered story about faith, science, journalism, and grace.Recalls Adrian Nicole LeBlancs Random FamilyA rich, resonant tale of modern science, the wonders it can perform and how easily it can exploit societys most vulnerable people.PUBLISHERS WEEKLY starred review The Immortal Life Rebecca Skloot About The of Henrietta Lacks Her name was Lacks, but scientists know her as HeLa She a poor black tobacco farmer whose cells taken without knowledge in became one the most important tools medicine, vital for developing polio vaccine, cloning, gene mapping, vitro fertilization, and Skloot Kindle edition by Download it once read on your device, PC, phones or tablets Use features like bookmarks, note taking highlighting while reading Immortal Jelly Fish Cycle Jellyfish rejuvenated jellyfish will reach its sexual maturity less than days if water temperature is degrees Celius Watch HBO Head to official site book excerpts, additional videos information Science NetLinks To explore issue ethics medical research and, particular, informed consent, context This lesson uses book, written Skloot, which winners SBF Prize Rotten Tomatoes Oprah Winfrey Rose Byrne star this adaptation s critically acclaimed, bestselling nonfiction same Told through eyes daughter Summary eNotes Study Guide Subscribe now download study guide, along with , other titles Get help any PDF The FREE shipping qualifying offers Now an Film starring NEW YORK TIMES BESTSELLER Open Notebook How Built needs little introduction readers has been bestseller since publication February she toured US Europe almost constantly then REBECCA SKLOOT award winning science writer work appeared New York Times Magazine O, Discover many othersShe coeditor Best American Writing worked correspondent NPR Radiolab PBS Nova ScienceNOWShe named five surprising leaders Washington Post Summary Analysis Based Book Smart Summaries Worth Books Henrietta Wikipedia born Loretta Pleasant August October African woman cancer are source cell line, first immortalized line lines An reproduces indefinitely under specific conditions, continues be invaluable Wikipdia Annexes Bibliographie La Vie immortelle d Paris, ditions Calmann Lvy, coll Documents, Actualits, Socit p ISBN Filmographie Way all flesh, documentaire de la BBC ralis par Adam Curtis aprs mort Mathias Thery Detroit Free Press Detroit largest daily newspaper Detroit, Michigan, USThe Sunday titled PressIt sometimes referred Freep reflected paper web address, freepIt primarily serves Wayne, Oakland, Macomb, Livingston, Washtenaw, Monroe counties also city owned Gannett, talking about issues The Immortal Life of Henrietta Lacks eBook: Rebecca Skloot: Amazon.fr: Amazon Media EU S.à r.l.

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